Tranexamic acid - cost effective method in preventing blood loss in total knee replacement
نویسندگان
چکیده
منابع مشابه
Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement
BACKGROUND & PURPOSE Allogenic blood transfusion in elective orthopaedic surgery is best avoided owing to its associated risks. Total knee replacement often requires blood transfusion, more so when bilateral surgery is performed. Many strategies are currently being employed to reduce the amount of peri-operative allogenic transfusions. Anti-fibrinolytic compounds such as aminocaproic acid and t...
متن کاملTranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement.
BACKGROUND Total knee arthroplasty (TKA) is often carried out using a tourniquet and shed blood is collected in drains. Tranexamic acid decreases the external blood loss. Some blood loss may be concealed, and the overall effect of tranexamic acid on the haemoglobin (Hb) balance is not known. METHODS Patients with osteoarthrosis had unilateral cemented TKA using spinal anaesthesia. In a double...
متن کاملWhich Route of Tranexamic Acid Administration is More Effective to Reduce Blood Loss Following Total Knee Arthroplasty?
Background: The most appropriate route of tranexamic acid administration is controversial. In the current study, we compared the efficacy of intravenous (IV) and topical intra-articular tranexamic acid in reducing blood loss and transfusion rate in patients who underwent primary total knee arthroplasty. Methods: One hundred twenty 120 patients were scheduled to undergo primary total knee arth...
متن کاملTopical Tranexamic Acid Reduces Blood Loss in Minimally Invasive Total Knee Arthroplasty Receiving Rivaroxaban
Background It is unclear whether topical (intra-articular) or intravenous TXA reduces blood loss in minimally invasive TKA patients receiving a direct oral anticoagulant for thromboprophylaxis. This study is to investigate whether TXA given intravenously or intra-articularly is effective in reducing blood loss in minimally invasive TKA patients using rivaroxaban for thromboprophylaxis. Method...
متن کاملEfficacy of tranexamic acid plus drain-clamping to reduce blood loss in total knee arthroplasty
BACKGROUND Perioperative blood loss is still an unsolved problem in total knee arthroplasty (TKA). The efficacy of the preoperative use of tranexamic acid (TXA) plus drain-clamping to reduce blood loss in TKA has been debated. This meta-analysis aimed to illustrate the efficacy of TXA plus drain-clamping to reduce blood loss in patients who underwent a TKA. METHODS In February 2017, a systema...
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ژورنال
عنوان ژورنال: International Journal of Advances in Medicine
سال: 2014
ISSN: 2349-3925
DOI: 10.5455/2349-3933.ijam20141107